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LVIS Blue as a Stand-alone “Flow Diverter”

Received: 26 December 2019     Accepted: 10 January 2020     Published: 4 February 2020
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Abstract

Flow diversion fundamentally changes the treatment approach towards intracranial aneurysms. Most currently available devices established efficacy and safety data in the proximal anterior circulation; the distal and posterior circulations remain areas of active research. LVIS Blue is a stent with 28% metal coverage approved for use as a coil adjuvant. Some studies indicate potential “flow diverter” properties. We sought to evaluate the LVIS Blue as a stand-alone “flow diverter” for the treatment of intracranial aneurysms. We performed an observational single-center study to evaluate initial occlusion and occlusion at six months follow-up for patients with distal or posterior circulation aneurysms treated with the LVIS Blue as a “flow diverter” at our institution. Ten aneurysms were treated over the course of two years with six-month angiographic follow-up. Seven lesions were in the distal anterior circulation and were unruptured (five anterior communicating artery, one M2 middle cerebral artery, one pericallosal). Three were posterior circulation (two basilar tip aneurysms, one P2 posterior cerebral artery aneurysm). Follow up demonstrated treatment effect in nine of ten aneurysms (four complete aneurysm occlusions, five lesions with decreased size and flow). One lesion showed no treatment response. No ischemic or hemorrhagic complications were noted during placement or clinical follow-up. LVIS Blue can function safely as a “flow diverter” in the distal and posterior circulations. Further data regarding long-term efficacy is needed.

Published in Clinical Neurology and Neuroscience (Volume 4, Issue 1)
DOI 10.11648/j.cnn.20200401.12
Page(s) 5-10
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2020. Published by Science Publishing Group

Keywords

Aneurysm, LVIS, Stent, Embolization, Flow Diverter

References
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[12] Raz E, Shapiro M, Becske T, et al. Anterior Choroidal Artery Patency and Clinical Follow-Up after Coverage with the Pipeline Embolization Device. American Journal of Neuroradiology. 2015; 36 (5): 937-942.
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Cite This Article
  • APA Style

    Matthew Koch, Mehr Nasir-Moin, Scott Raymond, Christopher Stapleton, Thabele Leslie-Mazwi, et al. (2020). LVIS Blue as a Stand-alone “Flow Diverter”. Clinical Neurology and Neuroscience, 4(1), 5-10. https://doi.org/10.11648/j.cnn.20200401.12

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    ACS Style

    Matthew Koch; Mehr Nasir-Moin; Scott Raymond; Christopher Stapleton; Thabele Leslie-Mazwi, et al. LVIS Blue as a Stand-alone “Flow Diverter”. Clin. Neurol. Neurosci. 2020, 4(1), 5-10. doi: 10.11648/j.cnn.20200401.12

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    AMA Style

    Matthew Koch, Mehr Nasir-Moin, Scott Raymond, Christopher Stapleton, Thabele Leslie-Mazwi, et al. LVIS Blue as a Stand-alone “Flow Diverter”. Clin Neurol Neurosci. 2020;4(1):5-10. doi: 10.11648/j.cnn.20200401.12

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  • @article{10.11648/j.cnn.20200401.12,
      author = {Matthew Koch and Mehr Nasir-Moin and Scott Raymond and Christopher Stapleton and Thabele Leslie-Mazwi and James Rabinov and Aman Patel},
      title = {LVIS Blue as a Stand-alone “Flow Diverter”},
      journal = {Clinical Neurology and Neuroscience},
      volume = {4},
      number = {1},
      pages = {5-10},
      doi = {10.11648/j.cnn.20200401.12},
      url = {https://doi.org/10.11648/j.cnn.20200401.12},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.cnn.20200401.12},
      abstract = {Flow diversion fundamentally changes the treatment approach towards intracranial aneurysms. Most currently available devices established efficacy and safety data in the proximal anterior circulation; the distal and posterior circulations remain areas of active research. LVIS Blue is a stent with 28% metal coverage approved for use as a coil adjuvant. Some studies indicate potential “flow diverter” properties. We sought to evaluate the LVIS Blue as a stand-alone “flow diverter” for the treatment of intracranial aneurysms. We performed an observational single-center study to evaluate initial occlusion and occlusion at six months follow-up for patients with distal or posterior circulation aneurysms treated with the LVIS Blue as a “flow diverter” at our institution. Ten aneurysms were treated over the course of two years with six-month angiographic follow-up. Seven lesions were in the distal anterior circulation and were unruptured (five anterior communicating artery, one M2 middle cerebral artery, one pericallosal). Three were posterior circulation (two basilar tip aneurysms, one P2 posterior cerebral artery aneurysm). Follow up demonstrated treatment effect in nine of ten aneurysms (four complete aneurysm occlusions, five lesions with decreased size and flow). One lesion showed no treatment response. No ischemic or hemorrhagic complications were noted during placement or clinical follow-up. LVIS Blue can function safely as a “flow diverter” in the distal and posterior circulations. Further data regarding long-term efficacy is needed.},
     year = {2020}
    }
    

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    AU  - Matthew Koch
    AU  - Mehr Nasir-Moin
    AU  - Scott Raymond
    AU  - Christopher Stapleton
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    JO  - Clinical Neurology and Neuroscience
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    PB  - Science Publishing Group
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    AB  - Flow diversion fundamentally changes the treatment approach towards intracranial aneurysms. Most currently available devices established efficacy and safety data in the proximal anterior circulation; the distal and posterior circulations remain areas of active research. LVIS Blue is a stent with 28% metal coverage approved for use as a coil adjuvant. Some studies indicate potential “flow diverter” properties. We sought to evaluate the LVIS Blue as a stand-alone “flow diverter” for the treatment of intracranial aneurysms. We performed an observational single-center study to evaluate initial occlusion and occlusion at six months follow-up for patients with distal or posterior circulation aneurysms treated with the LVIS Blue as a “flow diverter” at our institution. Ten aneurysms were treated over the course of two years with six-month angiographic follow-up. Seven lesions were in the distal anterior circulation and were unruptured (five anterior communicating artery, one M2 middle cerebral artery, one pericallosal). Three were posterior circulation (two basilar tip aneurysms, one P2 posterior cerebral artery aneurysm). Follow up demonstrated treatment effect in nine of ten aneurysms (four complete aneurysm occlusions, five lesions with decreased size and flow). One lesion showed no treatment response. No ischemic or hemorrhagic complications were noted during placement or clinical follow-up. LVIS Blue can function safely as a “flow diverter” in the distal and posterior circulations. Further data regarding long-term efficacy is needed.
    VL  - 4
    IS  - 1
    ER  - 

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Author Information
  • Department of Neurosurgery, The Massachusetts General Hospital, Boston, The United States

  • Department of Neurosurgery, The Massachusetts General Hospital, Boston, The United States

  • Department of Radiology, The University of Vermont Medical Center, Burlington, The United States

  • Department of Neurosurgery, The Massachusetts General Hospital, Boston, The United States

  • Department of Neurosurgery, The Massachusetts General Hospital, Boston, The United States

  • Department of Neurosurgery, The Massachusetts General Hospital, Boston, The United States

  • Department of Neurosurgery, The Massachusetts General Hospital, Boston, The United States

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