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Cerebral Venous Thrombosis Post COVID 19 in Neurological Unit of Fann Teaching Hospital, Dakar – Senegal

Received: 12 November 2023     Accepted: 5 December 2023     Published: 11 January 2024
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Abstract

Introduction: The new coronavirus constitutes a public health problem due to its many often fatal complications such as thromboembolic diseases. Upper this infectious state, neurological diseases are reported mainly ischemic stroke and rarely cerebral venous thrombosis. Observation: We report the case of a 76-year-old diabetic, hypertensive patient who was well monitored and who presented neurological manifestations 24 hours after home returning from hospitalization for COVID 19 infection fifteen days before. Major signs were dehydration grade I according to the WHO, confusional syndrom, left pyramidal syndrom of cortical type predominantly on facial and arm and regular tachycardia. The brain imagery revealed a double thrombus in sinus and diagnosis of cerebral thrombosis (CVT) was made. Biological abnormalities were noted, such as neutrophilic hyperleukocytosis and thrombocytopenia. The evolution was favorable with symptomatic treatment and after putting on oral curative dosis anticoagulant. Conclusion: Cases of cerebral venous thrombosis are increasingly reported in the literature, but Cases of CVT in the field COVID 19 remain rare, especially in Africa. Elderly age and vascular risk factors could favorite occurrence of cerebral venous thrombosis in cases of Sars-Cov infection. It is important to think about it in the face of any brain neurological picture given the thrombogenic nature of COVID 19, mainly in geriatric population. However, guidelines must been done for better management of these patients even if outcomes evolution are generally favourable.

Published in Clinical Neurology and Neuroscience (Volume 8, Issue 1)
DOI 10.11648/j.cnn.20240801.12
Page(s) 8-11
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Cerebral Venous Thrombosis, New Coronavirus, Anticoagulant, Neurology, CHU Fann, Dakar, Senegal

References
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[2] Maatman TK, Jalali F, Feizpour C, Douglas 2nd A, McGuire SP, Kinnaman G, et al. Routine venous thromboembolism prophylaxis may be inadequate in the hypercoagulable state of severe coronavirus disease 2019. Crit Care Med 2020.
[3] Lodigiani C, Iapichino G, Carenzo L, Cecconi M, Ferrazzi P, Sebastian T, et al. Venous and arterial thromboembolic complications in COVID-19 patients admitted to an academic hospital in Milan, Italy. Thromb Res 2020; 191: 9-14.
[4] Bouguila Hajer, Ghachem Ichrak, Ameny Ameur, Brahim Syrine, Samia Younes. Les manifestations neurologiques de la pandémie COVID-19. Revue neurologique 2022; 178: S2-S139.
[5] Khan IH, Savarimuthu S, Tsun Leung MS, Harky A. The need to manage the risk of thromboembolism in COVID-19 patients. J Vasc Surg. 2020; 5. https://doi.org/10.1016/j. jvs.2020.05.015.
[6] Tian Ming Tu, Claire Goh, Ying Kiat Tan. Cerebral Venous Thrombosis in Patients with COVID-19 Infection: A Case Series and Systematic Review. Journal of Stroke and Cerebrovascular Diseases, Vol. 29, No. 12 (December), 2020: 105379.
[7] Flis-Richard H., Verdonk F. Atteintes neurologiques dans l’infection du SARS-CoV-2 (COVID-19). Le Praticien en anesthésie réanimation (2020) 24, 186-189
[8] Katarina Dakay DO, Jared Cooper, Jessica Bloomfield. Cerebral Venous Sinus Thrombosis in COVID-19 Infection: A Case Series and Review of The Literature; Journal of Stroke and Cerebrovascular Diseases, Vol. 30, No. 1 (January), 2021: 105434.
[9] Li Y, Wang M, Zhou Y. Acute cerebrovascular disease following COVID-19: a single center, retrospective, observational study. SSRN Electron J 2020.
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[11] Varatharaj A, Thomas N, Ellul MA, Davies NWS, Pollak TA, Tenorio EL, et al. Neurological and neuropsychiatric complications of COVID-19 in 153 patients: a UK-wide surveillance study. Lancet Psychiatry 2020; 0, http://dx.doi.org/10.1016/S2215-0366(20)30287-X.
[12] Helms J, Kremer S, Merdji H, Clere-Jehl R, Schenck M, Kummerlen C, et al. Neurologic features in severe SARS-CoV-2 infection. N Engl J Med 2020; 382: 2268-70.
[13] Hughes C, Nichols T, Pike M, Subbe C, Elghenzai S. Cerebral venous sinus thrombosis as a presentation of COVID-19. Eur J Case Rep Intern Med 2020; 7 (5): 001691.
[14] Ferro JM, Bousser MG, Canhao P, et al. European stroke organization guideline for the diagnosis and treatment of cerebral venous thrombosis – endorsed by the European academy of neurology. Eur Stroke J 2017; 2: 195-221.
[15] Costa A, Weinstein ES, Sahoo DR, et al. How to build the plane while flying: VTE/PE thromboprophylaxis clinical guidelines for COVID-19 patients. Disaster Med Public Health Prep 2020; 1-15.
[16] Ghosh R., Roy D., Mandal A. et al. Cerebral venous thrombosis in COVID-19. Diabetes & Metabolic Syndrome: Clinical Research & Reviews 2021; 15: 1039-1045.
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  • APA Style

    Sow, A. D., Basse, A. M., Mansoj, H. M., Fall, A. A., Gaye, N. M., et al. (2024). Cerebral Venous Thrombosis Post COVID 19 in Neurological Unit of Fann Teaching Hospital, Dakar – Senegal. Clinical Neurology and Neuroscience, 8(1), 8-11. https://doi.org/10.11648/j.cnn.20240801.12

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    ACS Style

    Sow, A. D.; Basse, A. M.; Mansoj, H. M.; Fall, A. A.; Gaye, N. M., et al. Cerebral Venous Thrombosis Post COVID 19 in Neurological Unit of Fann Teaching Hospital, Dakar – Senegal. Clin. Neurol. Neurosci. 2024, 8(1), 8-11. doi: 10.11648/j.cnn.20240801.12

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    AMA Style

    Sow AD, Basse AM, Mansoj HM, Fall AA, Gaye NM, et al. Cerebral Venous Thrombosis Post COVID 19 in Neurological Unit of Fann Teaching Hospital, Dakar – Senegal. Clin Neurol Neurosci. 2024;8(1):8-11. doi: 10.11648/j.cnn.20240801.12

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  • @article{10.11648/j.cnn.20240801.12,
      author = {Adjaratou Dieynabou Sow and Anna Modji Basse and Halladain Mpung Mansoj and Abdou Aziz Fall and Ndiaga Matar Gaye and Marième Soda Diop and Maouly Fall and Ngor Side Diagne and Lala Bouna Seck and Kamadore Touré and Moustapha Ndiaye and Amadou Gallo Diop},
      title = {Cerebral Venous Thrombosis Post COVID 19 in Neurological Unit of Fann Teaching Hospital, Dakar – Senegal},
      journal = {Clinical Neurology and Neuroscience},
      volume = {8},
      number = {1},
      pages = {8-11},
      doi = {10.11648/j.cnn.20240801.12},
      url = {https://doi.org/10.11648/j.cnn.20240801.12},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.cnn.20240801.12},
      abstract = {Introduction: The new coronavirus constitutes a public health problem due to its many often fatal complications such as thromboembolic diseases. Upper this infectious state, neurological diseases are reported mainly ischemic stroke and rarely cerebral venous thrombosis. Observation: We report the case of a 76-year-old diabetic, hypertensive patient who was well monitored and who presented neurological manifestations 24 hours after home returning from hospitalization for COVID 19 infection fifteen days before. Major signs were dehydration grade I according to the WHO, confusional syndrom, left pyramidal syndrom of cortical type predominantly on facial and arm and regular tachycardia. The brain imagery revealed a double thrombus in sinus and diagnosis of cerebral thrombosis (CVT) was made. Biological abnormalities were noted, such as neutrophilic hyperleukocytosis and thrombocytopenia. The evolution was favorable with symptomatic treatment and after putting on oral curative dosis anticoagulant. Conclusion: Cases of cerebral venous thrombosis are increasingly reported in the literature, but Cases of CVT in the field COVID 19 remain rare, especially in Africa. Elderly age and vascular risk factors could favorite occurrence of cerebral venous thrombosis in cases of Sars-Cov infection. It is important to think about it in the face of any brain neurological picture given the thrombogenic nature of COVID 19, mainly in geriatric population. However, guidelines must been done for better management of these patients even if outcomes evolution are generally favourable.
    },
     year = {2024}
    }
    

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    AU  - Adjaratou Dieynabou Sow
    AU  - Anna Modji Basse
    AU  - Halladain Mpung Mansoj
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    AU  - Ndiaga Matar Gaye
    AU  - Marième Soda Diop
    AU  - Maouly Fall
    AU  - Ngor Side Diagne
    AU  - Lala Bouna Seck
    AU  - Kamadore Touré
    AU  - Moustapha Ndiaye
    AU  - Amadou Gallo Diop
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    AB  - Introduction: The new coronavirus constitutes a public health problem due to its many often fatal complications such as thromboembolic diseases. Upper this infectious state, neurological diseases are reported mainly ischemic stroke and rarely cerebral venous thrombosis. Observation: We report the case of a 76-year-old diabetic, hypertensive patient who was well monitored and who presented neurological manifestations 24 hours after home returning from hospitalization for COVID 19 infection fifteen days before. Major signs were dehydration grade I according to the WHO, confusional syndrom, left pyramidal syndrom of cortical type predominantly on facial and arm and regular tachycardia. The brain imagery revealed a double thrombus in sinus and diagnosis of cerebral thrombosis (CVT) was made. Biological abnormalities were noted, such as neutrophilic hyperleukocytosis and thrombocytopenia. The evolution was favorable with symptomatic treatment and after putting on oral curative dosis anticoagulant. Conclusion: Cases of cerebral venous thrombosis are increasingly reported in the literature, but Cases of CVT in the field COVID 19 remain rare, especially in Africa. Elderly age and vascular risk factors could favorite occurrence of cerebral venous thrombosis in cases of Sars-Cov infection. It is important to think about it in the face of any brain neurological picture given the thrombogenic nature of COVID 19, mainly in geriatric population. However, guidelines must been done for better management of these patients even if outcomes evolution are generally favourable.
    
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Author Information
  • Department of Neurology, Fann National Teaching Hospital, Dakar, Senegal

  • Department of Neurology, Fann National Teaching Hospital, Dakar, Senegal

  • Department of Neurology, Fann National Teaching Hospital, Dakar, Senegal

  • Department of Neurology, Fann National Teaching Hospital, Dakar, Senegal

  • Department of Neurology, Fann National Teaching Hospital, Dakar, Senegal

  • Department of Neurology, Fann National Teaching Hospital, Dakar, Senegal

  • Department of Neurology, Fann National Teaching Hospital, Dakar, Senegal

  • Department of Neurology, Fann National Teaching Hospital, Dakar, Senegal

  • Department of Neurology, Fann National Teaching Hospital, Dakar, Senegal

  • Department of Neurology, Fann National Teaching Hospital, Dakar, Senegal

  • Department of Neurology, Fann National Teaching Hospital, Dakar, Senegal

  • Department of Neurology, Fann National Teaching Hospital, Dakar, Senegal

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