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Risk Factors for Stroke Associated with HIV at Loandjili General Hospital in Pointe-Noire (Congo)

Received: 3 November 2021     Accepted: 19 November 2021     Published: 27 November 2021
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Abstract

Introduction: HIV infection and stroke constitute a major public health problem due to their morbidity and mortality. In people living with HIV the risk of developing a stroke is high. Objective: To establish the causal link between HIV and the onset of stroke in order to determine the risk factors for stroke associated with HIV at loandjili general hospital. Patients and Methods: It was a case-control study, prospective from January to July 2019, carried out in the department of Pointe-Noire, including any patient hospitalized for stroke confirmed by brain scan, any patient hospitalized or coming for an outpatient consultation. pathologies unrelated to stroke. The statistical analysis was carried out using the EPI info 7.2 software. Results: Two hundred patients were included in our study, including 100 cases and 100 controls. The relative frequency of HIV was 17% in cases versus 43% in controls. Young age was the risk factor for stroke associated with HIV. This risk factor was potentiated by immunosuppression of CD4 + T lymphocytes. Seventy-eight (78%) of stroke + / HIV + patients had a CD4 + count <200 / mm3. DALY was the predominant mechanism of injury with a frequency of 56% in people living with HIV. Conclusion: Stroke-HIV co-morbidity is frequent in Pointe-Noire. The risk factors for stroke / HIV + are dominated by young age. However, our study did not show a causal link between HIV and the onset of stroke.

Published in Clinical Neurology and Neuroscience (Volume 5, Issue 4)
DOI 10.11648/j.cnn.20210504.16
Page(s) 111-116
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2021. Published by Science Publishing Group

Keywords

Stroke, HIV, Case-controls, Pointe Noire, Congo

References
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Cite This Article
  • APA Style

    Prince Eliot Galieni Sounga Bandzouzi, Ghislain Armel Mpandzou, Raissa Mayanda, Josué Euberma Diatewa, Patience Moudeko M’foutou, et al. (2021). Risk Factors for Stroke Associated with HIV at Loandjili General Hospital in Pointe-Noire (Congo). Clinical Neurology and Neuroscience, 5(4), 111-116. https://doi.org/10.11648/j.cnn.20210504.16

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    ACS Style

    Prince Eliot Galieni Sounga Bandzouzi; Ghislain Armel Mpandzou; Raissa Mayanda; Josué Euberma Diatewa; Patience Moudeko M’foutou, et al. Risk Factors for Stroke Associated with HIV at Loandjili General Hospital in Pointe-Noire (Congo). Clin. Neurol. Neurosci. 2021, 5(4), 111-116. doi: 10.11648/j.cnn.20210504.16

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    AMA Style

    Prince Eliot Galieni Sounga Bandzouzi, Ghislain Armel Mpandzou, Raissa Mayanda, Josué Euberma Diatewa, Patience Moudeko M’foutou, et al. Risk Factors for Stroke Associated with HIV at Loandjili General Hospital in Pointe-Noire (Congo). Clin Neurol Neurosci. 2021;5(4):111-116. doi: 10.11648/j.cnn.20210504.16

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  • @article{10.11648/j.cnn.20210504.16,
      author = {Prince Eliot Galieni Sounga Bandzouzi and Ghislain Armel Mpandzou and Raissa Mayanda and Josué Euberma Diatewa and Patience Moudeko M’foutou and Dina Happia Motoula-latou and Charles Godefroy Koubemba and Paul Macaire Ossou-nguiet and Donatien Moukassa},
      title = {Risk Factors for Stroke Associated with HIV at Loandjili General Hospital in Pointe-Noire (Congo)},
      journal = {Clinical Neurology and Neuroscience},
      volume = {5},
      number = {4},
      pages = {111-116},
      doi = {10.11648/j.cnn.20210504.16},
      url = {https://doi.org/10.11648/j.cnn.20210504.16},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.cnn.20210504.16},
      abstract = {Introduction: HIV infection and stroke constitute a major public health problem due to their morbidity and mortality. In people living with HIV the risk of developing a stroke is high. Objective: To establish the causal link between HIV and the onset of stroke in order to determine the risk factors for stroke associated with HIV at loandjili general hospital. Patients and Methods: It was a case-control study, prospective from January to July 2019, carried out in the department of Pointe-Noire, including any patient hospitalized for stroke confirmed by brain scan, any patient hospitalized or coming for an outpatient consultation. pathologies unrelated to stroke. The statistical analysis was carried out using the EPI info 7.2 software. Results: Two hundred patients were included in our study, including 100 cases and 100 controls. The relative frequency of HIV was 17% in cases versus 43% in controls. Young age was the risk factor for stroke associated with HIV. This risk factor was potentiated by immunosuppression of CD4 + T lymphocytes. Seventy-eight (78%) of stroke + / HIV + patients had a CD4 + count <200 / mm3. DALY was the predominant mechanism of injury with a frequency of 56% in people living with HIV. Conclusion: Stroke-HIV co-morbidity is frequent in Pointe-Noire. The risk factors for stroke / HIV + are dominated by young age. However, our study did not show a causal link between HIV and the onset of stroke.},
     year = {2021}
    }
    

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  • TY  - JOUR
    T1  - Risk Factors for Stroke Associated with HIV at Loandjili General Hospital in Pointe-Noire (Congo)
    AU  - Prince Eliot Galieni Sounga Bandzouzi
    AU  - Ghislain Armel Mpandzou
    AU  - Raissa Mayanda
    AU  - Josué Euberma Diatewa
    AU  - Patience Moudeko M’foutou
    AU  - Dina Happia Motoula-latou
    AU  - Charles Godefroy Koubemba
    AU  - Paul Macaire Ossou-nguiet
    AU  - Donatien Moukassa
    Y1  - 2021/11/27
    PY  - 2021
    N1  - https://doi.org/10.11648/j.cnn.20210504.16
    DO  - 10.11648/j.cnn.20210504.16
    T2  - Clinical Neurology and Neuroscience
    JF  - Clinical Neurology and Neuroscience
    JO  - Clinical Neurology and Neuroscience
    SP  - 111
    EP  - 116
    PB  - Science Publishing Group
    SN  - 2578-8930
    UR  - https://doi.org/10.11648/j.cnn.20210504.16
    AB  - Introduction: HIV infection and stroke constitute a major public health problem due to their morbidity and mortality. In people living with HIV the risk of developing a stroke is high. Objective: To establish the causal link between HIV and the onset of stroke in order to determine the risk factors for stroke associated with HIV at loandjili general hospital. Patients and Methods: It was a case-control study, prospective from January to July 2019, carried out in the department of Pointe-Noire, including any patient hospitalized for stroke confirmed by brain scan, any patient hospitalized or coming for an outpatient consultation. pathologies unrelated to stroke. The statistical analysis was carried out using the EPI info 7.2 software. Results: Two hundred patients were included in our study, including 100 cases and 100 controls. The relative frequency of HIV was 17% in cases versus 43% in controls. Young age was the risk factor for stroke associated with HIV. This risk factor was potentiated by immunosuppression of CD4 + T lymphocytes. Seventy-eight (78%) of stroke + / HIV + patients had a CD4 + count <200 / mm3. DALY was the predominant mechanism of injury with a frequency of 56% in people living with HIV. Conclusion: Stroke-HIV co-morbidity is frequent in Pointe-Noire. The risk factors for stroke / HIV + are dominated by young age. However, our study did not show a causal link between HIV and the onset of stroke.
    VL  - 5
    IS  - 4
    ER  - 

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Author Information
  • Faculty of Health Sciences, Marien N’GOUABI University, Brazzaville, Republic of Congo

  • Faculty of Health Sciences, Marien N’GOUABI University, Brazzaville, Republic of Congo

  • Faculty of Health Sciences, Marien N’GOUABI University, Brazzaville, Republic of Congo

  • Faculty of Health Sciences, Marien N’GOUABI University, Brazzaville, Republic of Congo

  • Department of Neurology, Loandjili General Hospital, Pointe-Noire, Republic of the Congo

  • Faculty of Health Sciences, Marien N’GOUABI University, Brazzaville, Republic of Congo

  • Department of Neurology, Loandjili General Hospital, Pointe-Noire, Republic of the Congo

  • Faculty of Health Sciences, Marien N’GOUABI University, Brazzaville, Republic of Congo

  • Faculty of Health Sciences, Marien N’GOUABI University, Brazzaville, Republic of Congo

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